The Food Experience butchers and delicatessen in Wine Street car park, which has been there for a number of years closed on Saturday.
However, the retail shop is just part of a business which also includes the production of readymade meals and a catering service and these will continue.
It is understood that to comply with more stringent regulations in relation to food production the operation had to be moved to a larger premises in Carrick-on-Shannon, where readymade meals for other shops and food for the catering service will continue to be produced.
Meanwhile, Ruby Lane, a ladies wear shop located in Johnston Court shopping centre off O’Connell Street in Sligo, also closed its doors on Saturday.
It had been open for around two years but a spokesperson for the store said that the closure was due to the scale of competition in the ladies wear sector, not just locally, but, increasingly, online.
The well known Hennigan’s bar on Wine Street, which had been leased, is also currently closed.
The most recent operator has confirmed that his lease is up and he will not be renewing it.
However, it may re-open under new management.